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Publications depuis 2007

 

 

 

 

Articles de synthèse

 

  • Le Lamer M, Pellerin L, Reynier M, Cau L, Pendaries V, Leprince C, Méchin MC, Serre G, Paul C, Simon M. Defects of corneocyte structural proteins and epidermal barrier in atopic dermatitis.
    doi: 10.1515/hsz-2015-0141.
    Biol Chem in press 2015.
    article
  • Girolomoni G, Griffiths CEM, Krueger J, Nestle FO, Nicolas J-F, Prinz JC, Puig L, Ståhle M, van de Kerkhof PCM, Allez M, Emery P, Paul C. Early intervention in psoriasis and immune-mediated inflammatory diseases: a hypothesis paper.
    doi: 10.3109/09546634.2014.880396.
    J Dermatol Treat in press 2015.
    article
  • Sebbag M, Serre G, Simon M. Filaggrin is expressed in the epithelial cells of the buccal mucosae.
    Pediatr Allergy Immunol 25:600-601, 2014.
    article
  • Kezic S, Novak N, Jakasa I, Jungersted JM, Simon M, Brandner JM, Middlekamp-Hub MA, Weidinger S. Skin barrier in atopic dermatis.
    Frontiers in bioscience 19:541-556, 2014.
    article
  • Simon M, Pellerin L, Pendaries V, Hsu C-Y, Mazereeuw-Hautier J, Paul C, Serre G, Jonca N.Le complexe de différenciation épidermique 
    Quoi de neuf ?
    In Biologie cutanée, Peau et Vésicules (dans tous leurs états) , M. Haftek. Editions Matrix, LYON, pp162-189, 2014.

  • Henry J, Leclerc E, Mazereeuw-Hautier J, Serre G, Simon M, Jonca N. L’enveloppe cornée : carapace du cornéocyte.
    Biologie Cutanée M. Haftek. Editions Matrix, LYON, 2012, pp, 2013.

  • Simon M, La dermatite atopique est-elle toujours associée à une altération de la barrière épidermique ?
    Rev Fr Allergol 53 : 125-128, 2013.

  • Takahara H, Serre G, Simon M. Deimination in skin and regulation of peptidyl-arginine deiminase expression in keratinocytes.
    In Protein Deimination in Health and Disease, A Nicholas Ed, Springer, NEW YORK, pp , 2013.

  • Ying S, Simon M, Serre G, Takahara H. Peptidylarginine Deiminases and Protein Deimination in Skin Physiopathology.
    In Psoriasis - a systemic disease, J O’Daly Ed, InTech – Open access publisher, ISBN 978-953-51-0281-6 RIJEKA, pp 117-132, 2012.

  • Girolomoni G, Mrowietz U, Paul C. Psoriasis: rationale for targeting IL-17.
    Br J Dermatol167:717-724, 2012.
    article
  • Henry J, Toulza E, Hsu C-Y, Pellerin L, Balica S, Mazereeuw-Hautier J, Paul C, Serre G,  Jonca N, Simon M. Update on the Epidermal Differentiation Complex.
    Frontiers in Bioscience 17:1517-1532, 2012.
    article
  • Méchin MC, Nachat R, Coudane F, Adoue V, Arnaud J, Serre G, Simon M. La désimination ou « citrullination » : une modification post-traductionnelle aux multiples facettes.
    Médecine/Sciences 27:49-54, 2011.
    article
  • Jonca N, Leclerc EA, Caubet C, Simon M, Guerrin M, Serre G. Corneodesmosomes and corneodesmosin: from the stratum corneum cohesion to the pathophysiology of genodermatoses.
    Eur J Dermatol 21:35-42, 2011.
    article
  • Caubet C, Jonca N, Leclerc E, Simon M, Guerrin M, Serre G. Cornéodesmosine – aspects fonctionnels.    
    In Biologie Cutanée – COBIP 2010, M. Haftek. Editions Matrix, LYON, pp117-132, 2011.

  • Montaudié H, Sbidian E, Paul C, Maza A, Gallini A, et al. Methotrexate in psoriasis: a systematic review of treatment modalities, incidence, risk factors and monitoring of liver toxicity.
    J Eur Acad Dermatol Venereol 25 Suppl 2:12-18, 2011.
    article
  • Prey S, Paul C, Bronsard V, Puzenat E, Gourraud PA, et al. Assessment of risk of psoriatic arthritis in patients with plaque psoriasis: a systematic review of the literature.
    J Eur Acad Dermatol Venereol 24Suppl 2:31-35, 2010.
    article
  • Jonca N, Caubet C, Guerrin M, Simon M, Serre G. Corneodesmosin: structure, function and involvement in pathophysiology.
    TODJ 4:36-45, 2010.

  • Chavanas S, Adoue V, Serre G, Simon M. Gene regulation at a distance in the epidermal keratinocyte: the paradigm of the PADI Gene locus.
    TODJ 4:21-26, 2010.

  • Simon M. The epidermal barrier structure and functions.
    TODJ 4:1-1, 2010.

  • Ying S, Dong S, Kawada A, Kojima T, Chavanas S, Méchin M-C, Adoue V, Serre G, Simon M, Takahara H. Transcriptional regulation of peptidylarginine deiminase expression in human keratinocytes.
    J Dermatol Sci 53:2-9, 2009.
    article
  • Jonca N, Caubet C, Guerrin M, Simon M, Serre G. Corneodesmosomal proteins.
    In Skin Moisturization 2nd edition, Rawlings AV, Leyden JJ Ed, Informa Healthcare, NEW YORK, pp 99-122, 2009.

  • Simon M, Chavanas S, Takahara H, Serre G. Peptidylarginine deiminases in skin biology.
    In Skin Moisturization 2nd edition, Rawlings AV, Leyden JJ Ed, Informa Healthcare, NEW YORK, pp 69-82, 2009.

  • Raymond A-A, Gonzalez de Peredo A, Stella A, Bouyssie D, Serre G, Monsarrat B, Simon M. Le protéome des corps lamellaires de l’épiderme.
    In Biologie Cutanée, M. Haftek. Editions Matrix, LYON, pp97-111, 2009.

  • Simon M. Tight junctions: new actors within the epidermal barrier.
    Keratin 12:16-19, 2007.

  • Simon M, Chavanas S, Méchin M-C, Nachat R, Adoue V, Arnaud J, Serre G. Enzymes de la couche cornée et hydratation cutanée.
    In Actualité en biologie cutanée, C. Dezutter-Dambuyant, D. Schmitt. Editions Eska, PARIS, pp30-33, 2007.

  • Méchin M-C, Sebbag M, Arnaud J, Nachat R, Foulquier C, Adoue V, Coudane F, Duplan H, Schmitt A-M, Chavanas S, Guerrin M, Serre G, Simon M. Update on peptidylarginine deiminases and deimination in skin physiology and severe human diseases.
    Int J Cosmet Sci 29:147-168, 2007.
    article
  • Simon M. De nouvelles actrices de la barrière épidermique : les jonctions serrées.
    Keratin 12:16-19, 2007.

 

Travaux originaux

 

  • Pendaries V, Le Lamer M, Cau L, Hansmann B, Malaisse J, Kezic S, Serre G, Simon M. In a three-dimensional reconstructed human epidermis filaggrin-2 is essential for proper cornification.
    Cell Death Dis 6, e1656, 2014.
    article
  • Pellerin L, Paul C, Schmitt AM, Serre G, Simon M. Bleomycin hydrolase down-regulation in lesional skin of adult atopic dermatitis patients is independent of FLG gene mutations.
    J Allergy Clin Immunol 134:1459-1461,2014.
    article
  • Pendaries-Rahoul V, Malaisse J, Pellerin L, Le Lamer M, Nachat R, Kezic S, Schmitt A-M, Paul C, Poumay Y, Serre G, Simon M. Knockdown of filaggrin in a three-dimensional reconstructed human epidermis impairs keratinocyte terminal differentiation.
    J Invest Dermatol 134:2938-2946, 2014.
    article
  • Mailhol C, Giordano-Labadie F, Lauwers-Cances V, Ammoury A, Paul C, Rancé F. Point prevalence and risk factors for food allergy in a cohort of 386 children with atopic dermatitis attending a multidisciplinary dermatology/pediatric allergy clinic.
    Eur J Dermatol 24:63-69, 2014.
    article
  • Fredonnet J, Gasc G, Serre G, Séverac C, Simon M. Topographical and nano-mechanical characterization of native corneocytes using atomic force microscopy.
    J Dermatol Sci 75:63-65, 2014.
    article
  • Hayez A, Malaisse J, Roegiers E, Reynier M, Renard C, Haftek M, Geenen V, Serre G, Simon M, Lambert de Rouvroit C, Michiels C, Poumay Y. High TMEM45A expression is correlated to epidermal keratinization.
    Exp Dermatol 23:339-344, 2014.
    article
  • Pellerin L, Henry J, Hsu CY, Balica S, Jean-Decoster C, Méchin MC, Hansmann B, Rodriguez E, Weindinger S, Schmitt AM, Serre G, Paul C, Simon M. Defects of filaggrin-like proteins in both lesional and non-lesional atopic skin. .
    J Allergy Clin Immunol 131:1094-1102, 2013.
    Selected by World Biomedical Frontiers / Allergy September-November-n°10, 2013.
    article
  • Escande H, Livideanu CB, Steiner A, Lahfa M, Marguery MC, Mazereeuw JH, Meyer N, Labadie F, Aquilina C, Viraben R, Gouraud PA, Paul C. Incidence and risk factors for treatment failure with infliximab in psoriasis.
    J Eur Acad Dermatol Venereol 27:1323-1324, 2013
    article
  • de Koning HD, van den Bogaard EH, Bergboer JGM, Kamsteeg M, van Vlijmen-Willems IMJJ, Hitomi K, Henry J, Simon M, Takashita N, Ishida-Yamamoto A, Schalkwijk J, Zeeuwen P.L.J.M. Expression profile of cornified envelope structural proteins and keratinocyte differentiation-regulating proteins during skin barrier repair.
    Br J Dermatol 166:1245-1254, 2012.
    article
  • Schmitt J, Spuls P, Boers M, Thomas K, Chalmers J, Roekevisch E, Paul C, et al. Towards global consensus on outcome measures for atopic eczema research: results of the HOME II meeting.
    Allergy 67:1111-1117, 2012.
    article
  • Gourraud PA, Le Gall C, Puzenat E, Aubin F, Ortonne JP, Paul C. Why statistics matter: limited inter-rater agreement prevents using the psoriasis area and severity index as a unique determinant of therapeutic decision in psoriasis.
    J Invest Dermatol 132:2171-2175, 2012.
    article
  • Viguier M, Aubin F, Delaporte E, Pagès C, Paul C, Beylot-Barry M, Goujon C, Rybojad M, Bachelez H. Efficacy and safety of tumor necrosis factor inhibitors in acute generalized pustular psoriasis.
    Arch Dermatol 148:1423-1425, 2012.
    article
  • Casas C, Paul C, Lahfa M, Livideanu B, Lejeune O, Alvarez-Georges S, Saint-Martory C, Degouy A, Mengeaud V, Ginisty H, Durbise E, Schmitt AM, Redoulès D. Quantification of Demodex folliculorum by PCR in rosacea and its relationship to skin innate immune activation.
    Exp Dermatol 21:906-910, 2012.
    article
  • Garrido Lagarrigue S, George J, Questel E, Lauze C, Meyer N, Lagarde JM, Simon M, Schmitt AM, Serre G, Paul C. In vivo quantification of epidermis pigmentation and dermis papilla density with reflectance confocal microscopy: variation with age and skin phototype.
    Exp Dermatol 21:281-286, 2012.
    article
  • Mazereeuw-Hautier J, Leclerc EA, Simon M, Serre G, Jonca N. A novel mutation in CDSN causes peeling skin disease in a patient from Morocco.
    Br J Dermatol 165:1152-1155, 2011.
    article
  • Coudane F, Méchin MC, Huchenq A, Henry J, Nachat R, Ishigami A, Adoue V, Sebbag M, Serre G, Simon M. Deimination and expression of peptidylarginine deiminases during cutaneous wound healing in mice.
    Eur J Dermatol 21:376-384, 2011.
    article
  • Hsu C-Y, Henry J, Raymond A-A, Méchin M-C, Pendaries V, Nassar D, Hansmann B, Balica S, Burlet-Schiltz O, Schmitt A-M, Takahara H, Paul C, Serre G, Simon M. Deimination of human filaggrin-2 promotes its proteolysis by calpain 1.
    J Biol Chem 286:23222-23233, 2011.
    article
  • Vasilopoulos Y, Sharaf N, di Giovine F, Simon M, Cork MJ, Duff GW, Tazi-Ahnini R. The 3’-UTR AACCins5874 in the stratum corneum chymotryptic enzyme gene (SCCE/KLK7), associated with atopic dermatitis, causes an increased mRNA expression without altering its stability.
    J Dermatol Sci 61:131-133, 2011.
    article
  • Henry J, Hsu CY, Haftek M, Nachat R, de Koning HD, Gardinal-Galera I, Hitomi K, Balica S, Jean-Decoster C, Schmitt AM, Paul C, Serre G, Simon M. Hornerin is a component of the epidermal cornified cell envelopes.
    FASEB J 25:1567-1576, 2011.
    article
  • Jonca N, Caubet C, Leclerc EA, Guerrin M, Simon M, Serre G. Protease sensitivity of corneodesmosin variants encoded by the six more common CDSN haplotypes.
    J Invest Dermatol 131:1381-1384, 2011.
    article
  • Paul C, Maumus-Robert S, Mazereeuw-Hautier J, Guyen CN, Saudez X, Schmitt AM. Prevalence and risk factors for xerosis in the elderly: a cross-sectional epidemiological study in primary care.
    Dermatology 223:260-5, 2011.
    article
  • Caubet C, Bousset L, Clemmensen O, Sourigues Y, Bygum A, Chavanas S, Coudane F, Hsu CY, Betz RC, Melki R, Simon M, Serre G. A new amyloidosis caused by fibrillar aggregates of mutated corneodesmosin.
    FASEB J 24:3416-3426, 2010.
    article
  • Ying S, Kojima T, Kawada A, Serre G, Simon M, Takahar H. An intronic enhancer driven by NF-κB contributes to transcriptional regulation of peptidylarginine deiminase type I gene in human keratinocytes.
    J Invest Dermatol 130: 2543-2552, 2010.
    article
  • Méchin MC, Coudane F, Adoue V, Arnaud J, Duplan H, Charveron M, Schmitt AM, Takahara H, Serre G, Simon M. Deimination is regulated at multiple levels including auto-deimination of peptidylarginine deiminases.
    Cell Mol Life Sci 67:1491-1503, 2010.
    article
  • Prey S, Paul C. Effect of folic or folinic acid supplementation on methotrexate-associated safety and efficacy in inflammatory disease: a systematic review.
    Br J Dermatol 160:622-628, 2009.

  • Mailhol C, Lauwers-Cances V, Rancé F, Paul C, Giordano-Labadie F. Prevalence and risk factors for allergic contact dermatitis to topical treatment in atopic dermatitis: a study in 641 children.
    doi: 10.1111/j.1398-9995.2008.01890.x
    Allergy 64:801-806, 2009.
    article
  • Adoue V, Chavanas S, Coudane F, Méchin M-C, Caubet C, Ying S, Dong S, Duplan H, Charveron M, Takahara H, Serre G, Simon M. Long range enhancer differentially regulated by c-jun and junD controls peptidylarginine deiminase-3 gene in keratinocytes.
    J Mol Biol 384:1048-1057, 2008.
    article
  • Chavanas S, Adoue V, Méchin M-C, Ying S, Dong S, Duplan H, Charveron M, Takahara H, Serre G, Simon M. Long-range enhancer associated with chromatin looping allows AP-1 regulation of the peptidylarginine deiminase 3 gene in differentiated keratinocyte.
    PLoS ONE 3:e3408, 2008.
    article
  • Dong S, Ying S, Kojima T, Shiraiwa M, Kawada A, Méchin M-C, Adoue V, Chavanas S, Serre G, Simon M, Takahara H. Crucial roles of MZF1 and Sp1 in the Transcriptional Regulation of the Peptidylarginine Deiminase Type I Gene (PADI1) in Human Keratinocytes.
    J Invest Dermatol 128:549-557, 2008.
    article
  • Raymond A-A, Gonzalez de Peredo A, Stella A, Ishida-Yamamoto A, Bouyssie D, Serre G, Monsarrat B, Simon M. Lamellar bodies of human epidermis: proteomics characterization by high-throughput mass spectrometry and possible involvement of CLIP 170 in their trafficking/secretion.
    Mol Cell Proteomics 7:2151-2175, 2008.
    article
  • Simon M, Tazi-Ahnini R, Jonca N, Caubet C, Cork M, Serre G. Alterations in the desquamation-related proteolytic cleavage of corneodesmosin and other corneodesmosomal proteins in psoriatic lesional epidermis.
    Br J Dermatol 159:77-85, 2008.
    article
  • Keilhoff G, Prell T, Langnaese K, Mawrin C, Simon M, Fansa H, Nicholas A-P. Expression pattern of peptidylarginine deiminases in rat and human Schwann cells.
    Dev Neurobiol 68:101-114, 2008.
    article
  • Foulquier C, Sebbag M, Clavel C, Chapuy-Regaud S, Al Badine R, Méchin M-C, Vincent C, Nachat R, Yamada M, Takahara H, Simon M, Guerrin M, Serre G. Peptidylarginine deiminase type 2 (PAD-2) and PAD-4 but not PAD-1, PAD-3 and PAD-6 are expressed in the rheumatoid arthritis synovium in close association with tissue inflammation.
    Arthritis Rheum 56:3541-3553, 2007.
    article
  • Raymond A-A, Méchin M-C, Nachat R, Toulza E, Tazi-Ahnini R, Serre G, Simon M. Nine procaspases are expressed in normal human epidermis, but only caspase-14 is fully processed.
    Br J Dermatol 156:420-427, 2007.
    article

 

 

 

 

 

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